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Low protein diets can lead to weight gain: new study

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Low protein diets can lead to weight gain: new studyPM - Low protein diets can lead to weight gain: new study 17/10/2011

MARK COLVIN: New research shows that low protein diets lead to overeating.

Australian researchers say they've found the first scientifically supported evidence that protein in the diet plays an important role in appetite and total food consumption.

Test subjects on a 10 per cent protein diet ate more snacks between meals and consumed significantly more calories in total than people on a 15 per cent protein diet.

The research has implications for continuing campaigns to reduce obesity in the population.

Brendan Trembath prepared this report.

BRENDAN TREMBATH: It's well known that obesity can be prevented through exercise.

(Sound of ball being hit)

Andrew Daniels and Ryo Taniguchi play a friendly game of tennis on a court at Sydney University.

And we know obesity can also be prevented by cutting calories - well not necessarily.

Dr Alison Gosby from the University of Sydney's School of Biological Sciences.

ALISON GOSBY: You can't just count the amount of calories that you're eating in a day. What you need to do is you need to actually maintain your protein intake as you would have and drop the rest of the energy intake by dropping the amount of fat and maybe simple sugars that you're eating.

BRENDAN TREMBATH: Dr Gosby and Professor Steve Simpson have published their protein research in the online journal PLoS ONE.

They began by recruiting 22 lean people.

ALISON GOSBY: We pretty much put an ad out for lean, healthy subjects. We had up to a 50-year-old but the age range was mainly from 21 through to 50, all healthy people.

BRENDAN TREMBATH: They were housed in apartments on campus.

ALISON GOSBY: So we put them in a facility that's made for doing studies such as these where they could basically go about their own thing during the day but they didn't have access to any outside food.

BRENDAN TREMBATH: The captive subjects were served three meals a day and snacks.

ALISON GOSBY: They'd have muesli and yoghurt for breakfast, a choice of muffins and often a different kind of banana bread or some kind of cake.

They'd then have a wrap for lunch with some salad and then main meals would be fairly similar - a pasta or a curry or something like that for dinner.

Then they'd also have some cakes or savoury scones or something like that, that would be available to them all day, that they could snack at if they were feeling hungry.

BRENDAN TREMBATH: Over time there were slight differences in the menus. The protein varied.

The researchers say they found the people on a 10 per cent protein diet ate more snacks between meals and consumed significantly more calories in total than the people on a 15 per cent protein diet.

ALISON GOSBY: Well they were allowed to eat as much as they want. They had so much food available to them, but they definitely ate more on the 10 per cent protein week.

BRENDAN TREMBATH: Dr Gosby says they'll do more research on protein and examine why some people don't get enough of it.

ALISON GOSBY: We're kind of being pushed to eating higher fat and carbohydrate foods rather than the protein foods.

BRENDAN TREMBATH: So do you mean for example if you look at a fast food menu the French fries might be a bit cheaper than the hamburger?

ALISON GOSBY: Yeah that's right and basically fast food is cheaper than going to make a healthy meal sometime. We're being forced to dilute the protein in our diet.

MARK COLVIN: Dr Alison Gosby from the University of Sydney with Brendan Trembath.
 
My thoughts, they should actually 'study' something worth while or educated themselves on nutrition. I'm surprised they didn't say to stop eating carbs at night as it will lead to weight loss, or eat 6 times a day to boost your metabolisum blah blah blah.

And as Bro mentioned, it is nothing new that a 'low protein' diet doesn't suppress appetite as much as a higher protein diet etc.
 
They are considering 15% as the high protein group. Hmm...

I think further research should be done to actually get to a diet that is considered high protein.

But as Bro said, I thought that was pretty much common knowledge these days.
 
Effect of a relatively high-protein, high-fi... [Eur J Clin Nutr. 2010] - PubMed - NCBI

Effect of a relatively high-protein, high-fiber diet on body composition and metabolic risk factors in overweight women.
Morenga LT, Williams S, Brown R, Mann J.
Source
Department of Human Nutrition, University of Otago, Dunedin, New Zealand. lisa.temorenga@otago.ac.nz
Abstract
BACKGROUND:
Obesity and its comorbidities are worldwide problems. Approaches to reducing obesity and its associated metabolic derangements typically emphasize fat and energy restriction, but for many achieving and maintaining weight loss is difficult. Diets that focus on substantially altering macronutrient distribution rather than energy restriction are promising alternatives, but have generally included large amounts of protein, fiber or fat.

OBJECTIVE:
To compare the effects of dietary advice including moderate increases in protein and fiber without specifying energy intake with standard low-fat, high-carbohydrate dietary recommendations on body composition and metabolic risk factors.Methods:89 overweight or obese women aged 18-65 years were randomized to either a standard diet that was intended to be low in fat and relatively high in carbohydrate (n=42) or to a relatively high-protein (up to 30% of energy), relatively high-fiber (>35g per day; HPHF) diet (n=47) for 10 weeks. Advice regarding strict adherence to energy intake goals was not given.

RESULTS:
Participants on the HPHF diet lost more body weight (1.3kg; 95% CI, 0.7, 1.9; P<0.0001), total fat (1.0kg; 95% CI, 0.2, 1.8; P<0.0001) and truncal fat (0.7kg; 95% CI, 0.1, 1.3; P=0.034) than participants on the standard diet. Total cholesterol and low-density lipoprotein (LDL) cholesterol were also significantly lower after the HPHF diet.

CONCLUSION:
An ad libitum diet relatively high in both protein and fiber improved body composition and metabolic risk factors compared with standard dietary advice.
 
Effect of an energy-restricted, high-protein,... [Am J Clin Nutr. 2005] - PubMed - NCBI

Effect of an energy-restricted, high-protein, low-fat diet relative to a conventional high-carbohydrate, low-fat diet on weight loss, body composition, nutritional status, and markers of cardiovascular health in obese women.
Noakes M, Keogh JB, Foster PR, Clifton PM.
Source
CSIRO Health Sciences and Nutrition, Adelaide, Australia. manny.noakes@csiro.au
Abstract
BACKGROUND:
Limited evidence suggests that a higher ratio of protein to carbohydrate during weight loss has metabolic advantages.

OBJECTIVE:
The objective was to evaluate the effects of a diet with a high ratio of protein to carbohydrate during weight loss on body composition, cardiovascular disease risk, nutritional status, and markers of bone turnover and renal function in overweight women.

DESIGN:
The subjects were randomly assigned to 1 of 2 isocaloric 5600-kJ dietary interventions for 12 wk according to a parallel design: a high-protein (HP) or a high-carbohydrate (HC) diet.

RESULTS:
One hundred women with a mean (+/-SD) body mass index (in kg/m(2)) of 32 +/- 6 and age of 49 +/- 9 y completed the study. Weight loss was 7.3 +/- 0.3 kg with both diets. Subjects with high serum triacylglycerol (>1.5 mmol/L) lost more fat mass with the HP than with the HC diet (x +/- SEM: 6.4 +/- 0.7 and 3.4 +/- 0.7 kg, respectively; P = 0.035) and had a greater decrease in triacylglycerol concentrations with the HP (-0.59 +/- 0.19 mmol/L) than with the HC (-0.03 +/- 0.04 mmol/L) diet (P = 0.023 for diet x triacylglycerol interaction). Triacylglycerol concentrations decreased more with the HP (0.30 +/- 0.10 mmol/L) than with the HC (0.10 +/- 0.06 mmol/L) diet (P = 0.007). Fasting LDL-cholesterol, HDL-cholesterol, glucose, insulin, free fatty acid, and C-reactive protein concentrations decreased with weight loss. Serum vitamin B-12 increased 9% with the HP diet and decreased 13% with the HC diet (P < 0.0001 between diets). Folate and vitamin B-6 increased with both diets; homocysteine did not change significantly. Bone turnover markers increased 8-12% and calcium excretion decreased by 0.8 mmol/d (P < 0.01). Creatinine clearance decreased from 82 +/- 3.3 to 75 +/- 3.0 mL/min (P = 0.002).

CONCLUSION:
An energy-restricted, high-protein, low-fat diet provides nutritional and metabolic benefits that are equal to and sometimes greater than those observed with a high-carbohydrate diet.
 
A randomized trial of a hypocaloric ... [Appl Physiol Nutr Metab. 2007] - PubMed - NCBI

A randomized trial of a hypocaloric high-protein diet, with and without exercise, on weight loss, fitness, and markers of the Metabolic Syndrome in overweight and obese women.
Meckling KA, Sherfey R.
Source
Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON N1G 2W1, Canada. kmecklin@uoguelph.ca
Abstract
The purpose of this study was to examine the effects of 3:1 and 1:1 carbohydrate to protein ratios, hypocaloric diets with and without exercise, and risk factors associated with the Metabolic Syndrome in overweight and obese Canadian women. Groups were designated as control diet (CON), control diet with exercise (CONEx), high-protein (HP), or high-protein with exercise (HPEx). Free-living women from the Guelph community were studied in a university health and fitness facility. The participants were 44 of 60 overweight and obese women who had been randomized to the 4 weight-loss programs. Habitual diets of the subjects were energy restricted and were to contain either a 1:1 or 3:1 ratio of carbohydrate to protein energy. Subjects either exercised 3 times/week or maintained their normal level of activity for 12 weeks. The main outcome measures were weight loss, blood lipids, blood pressure, insulin, body composition, nitrogen balance, fitness, and resting energy expenditure. All groups lost weight over the 12 week period: -2.1 kg for the CON group, -4.0 kg in the CONEx group, -4.6 kg in the HP group, and -7.0 kg in the HPEx. All participants exhibited improved body composition, decreased blood pressure, and decreased waist and hip circumference. Actual diets consumed by the subjects contained ratios of carbohydrate to protein of 3.0:1, 2.7:1, 1.5:1, and 0.96:1 for the CON, CONEx, HP, and HPEx groups, respectively. Cardiovascular fitness improved in both exercise groups. There were no changes in resting energy expenditure. No adverse events were reported. Significant changes in blood lipids included decreased total cholesterol in the HP and CONEx groups, decreased low-density lipoprotein cholesterol in the HP group only, and decreased blood triglycerides in the HPEx group only. High-density lipoprotein cholesterol, fasting blood glucose, and fasting insulin levels were unaltered by diet or exercise. A high-protein diet was superior to a low-fat, high-carbohydrate diet either alone or when combined with an aerobic/resistance-training program in promoting weight loss and nitrogen balance, while similarly improving body composition and risk factors for the Metabolic Syndrome in overweight and obese Canadian women.
 
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